Introduction
Local production of the alcohol-based handrub is an alternative to commercial products. Although adapted to contexts with limited resources, it is essential to respect the Good Manufacturing Practices to ensure the quality, efficacy and safety of the product.
Learning objectives
At the end of the lesson, you will be able to:
- Set up an alcohol-based handrub production in your facility
- Describe the various components of the WHO formulations
- Production of the alcohol-based handrub respecting the Good Manufacturing Practices
- Carry out a quality control of the solution
- Ensure the traceability of every batch produced
Format
This lesson is divided into 4 parts:
- Pre-assessment:
- e-learning lesson
- Post-assessment:
- course evaluation : satisfaction and learners' feedback
Investment time
Here you find the main resources for this module. More resources are available to download by clicking here
Guidelines and recommendations
- Guide to Local Production: WHO-recommended Handrub Formulations
- Alcohol-based Handrub Planning and Costing Tool
- Soap/Handrub Consumption Survey
Practical tools
- Tools related to production
- Production sheet (ABHR WHO formulation 1)
- production sheet WHO ABHR formulation 2 WHO (available soon)
- Commented slideshow of production steps
- Production report for ABHR WHO-formulation 1
- Production report for WHO ABHR formulation 2 (available soon)
- Component amounts based on initial alcohol concentration
- ABHR production operator training form
- ABHR bottles recycling and cleaning procedure
- Compliance and release from quarantine sheet
- Quarantine signaling sheet
- Checklist of equipment contained in WHO ABHR production and quality control kits for specialized health facilities
- Checklist of equipment contained in WHO ABHR production and quality control kits for non specialized health facilities
- Tools related to quality control
- Alcohol concentration measurement procedure
- Logbook alcohol concentration measurement
- Procedure of hydrogen peroxyde dosage by titration (specialised centres)
- Logbook hydrogen peroxyde titration
- Analytical reports for ABHR (alcoholmeter + titration)
- Hydrogen peroxyde semi-quantitative dosage procedure
- Logbook hydrogen peroxyde semi-quantitative dosage
- Analytical Report of the ABHR solution (alcoholmeter + semi-quantitative dosage)
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